Whole genome sequence and comparative analysis of Borrelia burgdorferi MM1
نویسندگان
چکیده
منابع مشابه
Sequence and phylogenetic analysis of the Borrelia burgdorferi secA gene.
A Borrelia burgdorferi secA homologue was cloned and the complete DNA sequence was determined. The deduced protein sequence consists of 899 amino acids and shows a high degree of homology to SecA homologues from other Bacteria and photosynthetic plastids. The presence of the secA gene in Spirochetes suggests that this gene is present in most if not all major lineages within Bacteria. The ease o...
متن کاملMicroarray-Based Comparative Genomic and Transcriptome Analysis of Borrelia burgdorferi
Borrelia burgdorferi, the spirochetal agent of Lyme disease, is maintained in nature in a cycle involving a tick vector and a mammalian host. Adaptation to the diverse conditions of temperature, pH, oxygen tension and nutrient availability in these two environments requires the precise orchestration of gene expression. Over 25 microarray analyses relating to B. burgdorferi genomics and transcri...
متن کاملWhole Genome Sequence and Comparative Genomics of the Novel Lyme Borreliosis Causing Pathogen, Borrelia mayonii
Borrelia mayonii, a Borrelia burgdorferi sensu lato (Bbsl) genospecies, was recently identified as a cause of Lyme borreliosis (LB) among patients from the upper midwestern United States. By microscopy and PCR, spirochete/genome loads in infected patients were estimated at 105 to 106 per milliliter of blood. Here, we present the full chromosome and plasmid sequences of two B. mayonii isolates, ...
متن کاملMultilocus sequence analysis of Borrelia burgdorferi s.l. in Russia.
Borrelia burgdorferi sensu lato is a species complex that includes the causative agents of Lyme borreliosis (LB). Classification of the complex was greatly influenced by the method of multilocus sequence typing (MLST), proposed in 2008 and analyzing the spatial distribution of sequence types (STs). Despite the fact that Russia is the largest natural focus of LB to date, it is represented by onl...
متن کاملComplete Genome Sequence of Borrelia afzelii K78 and Comparative Genome Analysis
The main Borrelia species causing Lyme borreliosis in Europe and Asia are Borrelia afzelii, B. garinii, B. burgdorferi and B. bavariensis. This is in contrast to the United States, where infections are exclusively caused by B. burgdorferi. Until to date the genome sequences of four B. afzelii strains, of which only two include the numerous plasmids, are available. In order to further assess the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0198135